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Define the Question - PICO
When performing research, begin by formulating a clinical question. Develop a clinical research question using PICO. Using a structured framework will help you to formulate a concise and focused research question so that you can build a more effective search.
Here is an example of a clinical question using PICO:
"In critical care patients, is there evidence to suggest that the use of pressure ulcer bundle interventions leads to a decline in the incidence of pressure ulcers in the critical care setting?"
Additional resources
Identifying Your Basic Search Terms and Concepts
Using PICO will help you to focus on your question's core concepts so that you can begin searching for keywords and subject headings that are relevant to your topic.
A thoughtful and comprehensive search uses both keywords and subject headings. Keep a table of the concepts, keywords, and subject heading terms you use as you perform your search. This will also help you to identify and build effective, repeatable search strategies as you research.
Example table: "What is the effectiveness of music therapy on stress levels in premature infants?"
The table above is simply a starting point. As you perform your search, you will find new keywords and subject headings to include/exclude. Searching is an iterative process that requires sorting and sifting through results, continuously refining your approach as you adjust the combination of words and search phrases that you use. It is not an instantaneous task, but an involved process. If you don't yield the results you want on the first try, keep trying until you find a sequence or combination of terms that work.
Librarian Recommendation: Watch this video for a fantastic tutorial of how to fill out your own PICO search grid and follow up with a search in CINAHL. PICO Searches in CINAHL by PNW Library
MeSH, or Medical Subject Headings, is the controlled vocabulary used by the National Library of Medicine to index articles for PubMed. MeSH, or controlled vocabulary terms:
For example, PubMed will auto-expand your keyword searches, mapping to corresponding MeSH terms. As shown below, the keyword "acid reflux" is automatically mapped to the MeSH heading "gastroesophageal reflux":
acid reflux: "gastroesophageal reflux"[MeSH Terms] OR ("gastroesophageal"[All Fields] AND "reflux"[All Fields]) OR "gastroesophageal reflux"[All Fields] OR ("acid"[All Fields] AND "reflux"[All Fields]) OR "acid reflux"[All Fields] |
When we enter the keyword "acid reflux," the system will search for the terms "acid" and "reflux," but it will also automatically perform a search for articles indexed under the MeSH term "gastroesophageal reflux."
Ideally, a comprehensive search combines both MeSH terms and keywords. View the chart below for a quick comparison between the two:
MeSH | Keywords |
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Boolean operators can help you to expand or refine your search. They allow you to bring together concepts in your research and refine them in a language that is recognized by the database your are searching. It is suggested that you capitalize AND, OR, and NOT to ensure that the database can interpret your search accurately.
AND - NARROWS your search.
OR - BROADENS your search.
NOT - NARROWS your search.
Combining Multiple Boolean Operators Together
You can link multiple concepts together using Boolean operators. For example, joining the concepts above:
(nutrition AND hypertension) AND (heart attack OR myocardial infarction)
will launch two search strategies simultaneously, yielding articles on nutrition and hypertension and then, among those articles, isolating only the ones that contain the terms heart attack or myocardial infarction. The end result is a set of articles on the topic of heart attacks in relation to nutrition and hypertension.
Truncation is a search strategy that helps you search for variations of a word.
Replace the end of a root word with a character. Databases can use the *, #, !, or ? as wildcard symbols.
For example:
child* = child, children, childhood...
teen* = teen, teenage, teenager...
Learn More: Truncating Search Terms in PubMed
Wildcard is similar to truncation except that you can use a symbol within a word to account for variation.
For example:
wom?n = woman, women
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